Human SNRPC peptide

Product Overview

Recombinant humanU1-snRNP C protein Full-length cDNA fused to a hexa-histidine purificationtag. Expressed by recombinant baculovirus (Autographa californica multiplenuclear polyhedrosis virus; AcMNPV) infection of Spodoptera frugiperda Sf9insect cells.

Nature

Recombinant

Tag/Conjugate

Unconjugated

Alternative Names

U1C; Yhc1

Purity

> 90%(SDS-PAGE)

Concentration

0.3–0.6μg/ml (depending on the type of ELISA plate and coating buffer). Suitable forbiotinylation and iodination.

Buffer

Neutralto slightly alkaline pH; due to purification workup under denaturingconditions presence of up to 0.02 % SDS (or similar detergents) may berequired for maintaining solubility.

Preservative

None

Storage

2-8°C short term, -20°C long term

Introduction

This protein is associated with snRNP U1.

Gene ID

6631

UniProt ID

P09234

Antigen Description

This gene encodesone of the specific protein components of the U1 small nuclearribonucleoprotein (snRNP) particle required for the formation of thespliceosome. The encoded protein participates in the processing of nuclearprecursor messenger RNA splicing. snRNP particles are attacked byautoantibodies frequently produced by patients with connective tissuediseases. The genome contains several pseudogenes of this functional gene.Alternative splicing results in a non-coding transcript variant.

Keywords

SNRPC; small nuclear ribonucleoprotein polypeptide C; U1 small nuclear ribonucleoprotein C; U1 C; Yhc1; U1 snRNP C; U1 snRNP protein C; U1 small nuclear RNP specific C; U1C; FLJ20302;