Rat CNP(C-Type Natriuretic Peptide) ELISA Kit

Aim: A retrospective study was conducted to explore the value of sentinel lymph node (SLN) mapping with carbon nanoparticles (CNP) in endometrial cancer patients. Methods: Seventy-six endometrial cancer patients who underwent sentinel lymph node mapping with or without systemic pelvic lymphadenectomy were involved in this study. All patients received cervical injection of carbon nanoparticles. The detection frequency for sentinel lymph nodes was calculated for all 76 patients, while the sensitivity and negative predictive value for metastasis were calculated for patients who underwent additional systemic pelvic lymphadenectomy (n=43). Clinical factors associated with sentinel lymph node detection were also evaluated. Results: The overall and bilateral detection frequencies were 71.1% (54/76) and 61.1% (33/54), respectively. A total of 291 sentinel lymph nodes were removed from 54 patients, with the median number removed per patient being 4 (range 3-7). sentinel lymph nodes were mostly located in the external lilac (45.7%) and obturator (41.2%) regions. Fifteen positive lymph nodes including 6 positive sentinel lymph nodes were found in 5 patients. Two of the five patients failed sentinel lymph node mapping but showed positive lymph nodes after systemic pelvic lymphadenectomy. The sensitivity and negative predictive value of sentinel lymph node mapping were therefore both 100%. Conclusion: The detection frequency of sentinel lymph node mapping with carbon nanoparticles in endometrial cancer patients was not as high as for some other cancer types. However, the accuracy of this method was high despite the relatively low detection frequency. More research is needed to improve sentinel lymph node mapping in endometrial cancer patients.

Most wetlands have been subject to changes in flooding regimes by climate change and human activities, resulting in widespread alteration of wetland plants at different organizational levels. However, scaling the responses of wetland plants to changes in flooding regimes is still challenging, because flooding could indirectly affect wetland plants through affecting environment factors (e.g. soil properties). During the non-flooding period, we investigated leaf N and P stoichiometry at three organizational levels (infra-species, inter-species, inter-community) along a flooding duration gradient in a lakeshore meadow of Poyang Lake floodplain, China. At the intra-species level, leaf N and P stoichiometry showed species-specific responses to flooding duration. At the inter-species level, leaf N or P contents or N:P ratio showed no significant response to flooding duration. At the inter-community level, leaf N and P contents significantly increased with flooding duration, while leaf N:P ratio decreased. At each organizational level, leaf N and P stoichiometry showed poor correlation with soil N and P stoichiometry. Moreover, intra-specific responses of leaf N and P contents to flooding duration and soil nutrient content increased with mean flooding duration of species distribution, which was the index of species hydrological niche. Intraspecific variation had lower contribution than species turnover to variations in community leaf nutrient stoichiometry. In all, flooding duration affected leaf N and P stoichiometry mainly through direct pathway at the intra-species and inter-community level, rather than the indirect pathway via soil nutrient stoichiometry. Therefore, our results have implications for scaling up from environmental conditions to ecosystem processes via wetland plant communities. (C) 2020 Elsevier B.V. All rights reserved.