Human RNF213 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-RNF213/C17orf27 (internal) antibody

Target

RNF213 / C17orf27 (internal)

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]

Function

ATPase activity; metal ion binding; nucleotide binding; ubiquitin-protein ligase activity; zinc ion binding;

Synonyms

RNF213; ring finger protein 213; C17orf27, chromosome 17 open reading frame 27 , KIAA1618 , moyamoya disease 2 , Moyamoya disease 2 , MYMY2; RING finger protein 213; KIAA1554; NET57; mysterin; ALK lymphoma oligomerization partner on chromosome 17; ALO17; MYMY2; MYSTR; C17orf27; KIAA1618; MGC9929; FLJ13051; MGC46622; DKFZp762N1115;