Specificity
Expressed ubiquitously but at low levels. Shows a strong expression in the erythrocytes.
Tag/Conjugate
Unconjugated
SequenceSimilarities
Contains 1 Rho-GAP domain.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Antigen Description
RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA; MIM 179550). Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS (MIM 601619), which in turn is activated by RAS (see HRAS; MIM 190020) (summary by Feig, 2003 [PubMed 12888294]).[supplied by OMIM, Nov 2010]
Function
ATPase activity; ATPase activity, coupled to movement of substances; GTPase activator activity; Rac GTPase activator activity; Rac GTPase binding; Ral GTPase binding; protein binding;
Synonyms
RALBP1; ralA binding protein 1; RIP1; RLIP1; RLIP76; ralA-binding protein 1; DNP-SG ATPase; ral-interacting protein 1; 76 kDa Ral-interacting protein; dinitrophenyl S-glutathione ATPase;
Citations
Publication ()
Have you cited DAG-P1058 in a publication?
Let us know and earn a reward for your research.