Product Overview
Blocking/Immunizing peptide for anti-RAD9A antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Function
3-5 exonuclease activity; SH3 domain binding; enzyme binding; exodeoxyribonuclease III activity; histone deacetylase binding; protein binding; protein kinase binding;
Synonyms
RAD9A; RAD9 homolog A (S. pombe); RAD9; cell cycle checkpoint control protein RAD9A; hRAD9; DNA repair exonuclease rad9 homolog A;
Citations
Publication ()
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