Human RAD51B blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-RAD51L1 antibody

Target

RAD51L1

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Jul 2011]

Function

ATP binding; DNA binding; DNA-dependent ATPase activity; double-stranded DNA binding; contributes_to four-way junction DNA binding; protein binding; single-stranded DNA binding;

Synonyms

RAD51B; RAD51 paralog B; REC2; R51H2; RAD51L1; DNA repair protein RAD51 homolog 2; RAD51 homolog B; RecA-like protein; recombination repair protein;