PURA peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

Belongs to the PUR DNA-binding protein family.

Purity

70 - 90% by HPLC.

Format

Liquid

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Entrez Gene ID

Antigen Description

This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq, Jul 2008]

Function

RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; SMAD binding; double-stranded telomeric DNA binding; poly(A) RNA binding; protein binding; purine-rich negative regulatory element binding; single-stranded DNA

Synonyms

PURA; purine-rich element binding protein A; PUR1; PURALPHA; PUR-ALPHA; transcriptional activator protein Pur-alpha; purine-rich single-stranded DNA-binding protein alpha;