Human PON3 peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

Belongs to the paraoxonase family.

Format

Liquid

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Entrez Gene ID

Antigen Description

This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described; however, only one has been fully characterized. [provided by RefSeq, Jul 2008]

Function

3,4-dihydrocoumarin hydrolase activity; aryldialkylphosphatase activity; arylesterase activity; arylesterase activity; dihydrocoumarin hydrolase activity; metal ion binding; protein homodimerization activity;

Synonyms

PON3; paraoxonase 3; serum paraoxonase/lactonase 3; paraoxanase-3; arylesterase 3;