The protein encoded by this gene is one of more than a dozen subunits forming eukaryotic RNA polymerase III (RNA Pol III), which transcribes 5S ribosomal RNA and tRNA genes. This protein has been shown to bind both TFIIIB90 and TBP, two subunits of RNA polymerase III transcription initiation factor IIIB (TFIIIB). Unlike most of the other RNA Pol III subunits, the encoded protein is unique to this polymerase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Function
DNA binding; DNA-directed RNA polymerase activity; contributes_to RNA polymerase III activity; protein binding
Synonyms
POLR3F; polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa; RPC6; RPC39; DNA-directed RNA polymerase III subunit RPC6; RNA polymerase III subunit C6; RNA polymerase III C39 subunit
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