Specifications
Immunogen
Synthetic peptide: LGLPYREPAERDW, corresponding to C terminal amino acids 563-571 of Human DNA polymerase lambda.
Applications
Application Notes
IHC-P: 5μg/ml
ELISA:>1:32000
Target
Alternative Names
POLL; polymerase (DNA directed), lambda; DNA polymerase lambda; BETA N; BETAN; DNA directed DNA polymerase lambda; DNA polymerase beta 2; DNA polymerase beta-2; DNA polymerase kappa; DNA polymerase kappa DNA polymerase beta N; DNA polymerase lambda; DNA polymerase lamda2; DPOLL_HUMAN; EC 2.7.7.7, EC 4.2.99.; FLJ46002; OTTHUMP00000020321; OTTHUMP00000020323; OTTHUMP00000059179; Pol beta2; POL KAPPA; Pol Lambda; POLKAPPA; POLL; Polymerase DNA directed lambda; DNA polymerase kappa; DNA polymerase beta-2; DNA polymerase beta-N; BETAN; POLKAPPA;
Product Background
Antigen Description
This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymerases, likely plays a role in non-homologous end joining and other DNA repair processes. Alternatively spliced transcript variants have been described.
Pathway
BER complex, organism-specific biosystem; BER complex, conserved biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Non-homologous end-joining, organism-specific biosystem; Non-homologous end-joining, conserved biosystem;
Citations
Publication ()
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