Product Overview
Blocking/Immunizing peptide for anti-PJA1 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes an enzyme that has E2-dependent E3 ubiquitin-protein ligase activity. This enzyme belongs to a class of ubiquitin ligases that include a RING finger motif, and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B. This gene is located in an area of chromosome X where several X-linked mental retardation disorders have been associated, and it has also been found as part of a contiguous gene deletion associated with craniofrontonasal syndrome, though a direct link to any disorder has yet to be demonstrated. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Function
ligase activity; metal ion binding; ubiquitin-protein ligase activity; zinc ion binding;
Synonyms
PJA1; praja ring finger 1, E3 ubiquitin protein ligase; praja 1 , praja ring finger 1; E3 ubiquitin-protein ligase Praja-1; FLJ11830; RNF70; praja 1; RING finger protein 70; PRAJA1;
Citations
Publication ()
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