This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. This protein is involved in lens formation during eye development. Mutations of this gene have been associated with anterior segment mesenchymal dysgenesis and congenital cataracts. [provided by RefSeq, Jul 2008]
Function
sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;
Synonyms
PITX3; paired-like homeodomain 3; paired like homeodomain transcription factor 3; pituitary homeobox 3; homeobox protein PITX3; PTX3; CTPP4; MGC12766;
Citations
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