Anti-PCNP polyclonal antibody (CABT-BL2864)

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant protein corresponding to amino acids of human PCNP.
Conjugate
Unconjugated

Applications


Application Notes
IHC: 1:50-1:200
WB: 1:250-1:500
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PCNP; PEST proteolytic signal containing nuclear protein; PEST proteolytic signal-containing nuclear protein; PEST-containing nuclear protein; DKFZp781I24156
Entrez Gene ID
UniProt ID

Citations


Have you cited CABT-BL2864 in a publication? Let us know and earn a reward for your research.

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

Customer Reviews


Write a review, share your experiences with others and get rewarded !
Product Name Cat. No. Applications Host Species Datasheet Price Add to Basket

References


LOCALIZATION AND CHARACTERISTICS OF ATRIAL-NATRIURETIC-PEPTIDE RECEPTORS IN PRENATAL AND POSTNATAL RAT-BRAIN

EUROPEAN JOURNAL OF PHARMACOLOGY

Authors: ZORAD, S; TSUTSUMI, K; BHATIA, AJ; SAAVEDRA, JM

We studied the expression of atrial natriuretic peptide (ANP) receptor subtypes during development in the rat forebrain, using quantitative autoradiography. Highest ANP binding was observed in the cortical neuroepithelium at embryonic day 17. Lower ANP binding was found in cingulate and frontal cortices at postnatal day 10, but none was detectable at 8 weeks of age. In the neuroepithelium of the embryonic rat, binding was displaced with a potency of rat ANP-(1-28) (rANP) > porcine type-C natriuretic peptide (pCNP-22) = rat ANP fragment C-ANP-(4-23) (rC-ANP-(4-23)) = rat brain natriuretic peptide (rBNP-32), different from that of any of the well-characterized (ANP(A), ANP(B), and ANP(C)) natriuretic peptide receptors. The present results support the hypothesis of a role for ANP during brain maturation and indicate that the ANP receptors highly expressed in the embryonic neuroepithelium may belong to a new ANP receptor subtype not yet characterized.

Lanthanum-Catalyzed Double Hydrophosphinylation of Nitriles

ORGANOMETALLICS

Authors: Basiouny, Miriam M. I.; Schmidt, Joseph A. R.

A new lanthanum-based catalyst was shown to be effective for the double hydrophosphinylation of unactivated nitriles under very mild conditions. Surprisingly, the lanthanum catalyst gave two regioisomeric products depending on the nature of the starting nitrile. Primary alkyl nitriles undergo 1,1-addition to give products with a new PCP linkage and concomitant formation of a primary amine. Under the same conditions, secondary alkyl and aryl nitriles instead produced 1,2-addition products, where 1 equiv of the phosphine oxide was added to the carbon, while a second equivalent added to the nitrogen of the nitrile, resulting in a PCNP framework. Further investigation of the catalytic cycle yielded evidence that all nitriles first undergo 1,1-addition (deemed the kinetic product) that then undergoes isomerization to the final unsymmetric addition product (the thermodynamic product). All catalytic reactions were run neat or with very little solvent, required little workup, and had high to moderate yields.

Online Inquiry

Name:
Phone: *
E-mail Address: *
Technology Interest:
Type of Organization:
Service & Products Interested: *
Project Description:

Related Products

Related Resources

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

Inquiry Basket