PARL blocking peptide (CDBP5888)

Synthetic PARL blocking peptide for IB Datasheet

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Nature
Synthetic
Immunogen
15 amino acids near the amino terminus of human PARL
Species Reactivity
Rat, human, mouse
Tag/Conjugate
Unconjugated
Format
Liquid
Concentration
200 μg/mL
Size
0.05mg
Storage
-20°C
UniProt ID
Antigen Description
This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Function
serine-type endopeptidase activity
Synonyms
PARL; presenilin associated, rhomboid-like; PSARL; PSARL1; RHBDS1; PRO2207; PSENIP2; presenilins-associated rhomboid-like protein, mitochondrial; rhomboid 7 homolog 1; mitochondrial intramembrane cleaving protease PARL; mitochondrial intramembrane-cleaving protease PARL

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