The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2013]
Function
ATP binding; cadmium ion binding; cobalt ion binding; copper ion binding; drug binding; extracellular ATP-gated cation channel activity; extracellular ATP-gated cation channel activity; identical protein binding; ligand-gated ion channel activity; mercury
Synonyms
P2RX2; purinergic receptor P2X, ligand-gated ion channel, 2; P2X2; DFNA41; P2X purinoceptor 2; ATP receptor; P2X Receptor, subunit 2;
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