Product Overview
Blocking/Immunizing peptide for anti-Neurotrophin 3 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq, Jul 2008]
Function
chemoattractant activity; growth factor activity; nerve growth factor binding; neurotrophin receptor binding; receptor binding;
Synonyms
NTF3; neurotrophin 3; NT3; HDNF; NGF2; NT-3; NGF-2; neurotrophin-3; neurotrophic factor; nerve growth factor 2;
Citations
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WILSON, C; ANGLMAYER, R; et al. MOLECULAR-CLONING, FUNCTIONAL EXPRESSION IN ESCHERICHIA-COLI, AND CHARACTERIZATION OF MULTIPLE MITOGEN-ACTIVATED-PROTEIN KINASES FROM TOBACCO. EUROPEAN JOURNAL OF BIOCHEMISTRY 233:249-257(1995).
Clement, TM; Bhandari, RK; et al. SRY Directly Regulates the Neurotrophin 3 Promoter During Male Sex Determination and Testis Development in Rats. BIOLOGY OF REPRODUCTION 85:277-284(2011).