Tag/Conjugate
Unconjugated
Antigen Description
Nucleoporins are proteins that play an important role in the assembly and functioning of the nuclear pore complex (NPC) which regulates the movement of macromolecules across the nuclear envelope (NE). The protein encoded by this gene plays a role in the fusion of NE vesicles and formation of the double membrane NE. The protein may also be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation. Alternative splicing results in multiple transcript variants of this gene. A pseudogene associated with this gene is located on chromosome 6. [provided by RefSeq, May 2013]
Function
structural constituent of nuclear pore; transporter activity
Synonyms
NUP155; nucleoporin 155kDa; N155; ATFB15; nuclear pore complex protein Nup155; nucleoporin 155kD; 155 kDa nucleoporin
Citations
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Wells, L; Vosseller, K; et al. Mapping sites of O-GlcNAc modification using affinity tags for serine and threonine post-translational modifications. MOLECULAR & CELLULAR PROTEOMICS 1:791-804(2002).
Gigliotti, S; Callaini, G; et al. Nup154, a new Drosophila gene essential for male and female gametogenesis is related to the Nup155 vertebrate nucleoporin gene. JOURNAL OF CELL BIOLOGY 142:1195-1207(1998).