This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways. [provided by RefSeq, Oct 2011]
Function
ATP binding; RNA polymerase II core promoter sequence-specific DNA binding; protein binding
Synonyms
NLRC5; NLR family, CARD domain containing 5; NOD4; NOD27; CLR16.1; protein NLRC5; NOD-like receptor C5; caterpiller protein 16.1; nucleotide-binding oligomerization domains 27; nucleotide-binding oligomerization domain protein 4; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 5
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