Product Overview
Blocking/Immunizing peptide for anti-NET1/ARHGEF8 (Internal) antibody
Target
NET1 / ARHGEF8 (Internal)
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]
Function
Rho guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity;
Synonyms
NET1; neuroepithelial cell transforming 1; neuroepithelial cell-transforming gene 1 protein; ARHGEF8; NET1A; proto-oncogene p65 Net1; p65 Net1 proto-oncogene protein; small GTP-binding protein regulator; neuroepithelioma transforming gene 1; neuroepithelial cell transforming gene 1; rho guanine nucleotide exchange factor 8; Rho guanine nucleotide exchange factor (GEF) 8; guanine nucleotide regulatory protein (oncogene);
Citations
Publication ()
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