Specifications
Immunogen
INPP5A (NP_005530, 288 a.a. ~ 388 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
Alternative Names
inositol polyphosphate-5-phosphatase, 40kDa; CTCL tumor antigen HD-CL-02; 5PTASE; inositol trisphosphate-5-phosphatase, 40kD; inositol polyphosphate-5-phosphatase, 40kD; InsP3 5-phosphatase; 43 kDa inositol polyphosphate 5-phophatase; type I inositol-1,4,
Product Background
Antigen Description
The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.
Mouse monoclonal antibody raised against a partial recombinant INPP5A.
Pathway
1D-myo-inositol hexakisphosphate biosynthesis II (mammalian), conserved biosystem; D-myo-inositol (1,3,4)-trisphosphate biosynthesis, conserved biosystem; D-myo-inositol (1,4,5)-trisphosphate degradation, conserved biosystem; Inositol phosphate metabolism, organism-specific biosystem; Inositol phosphate metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem.
Citations
Publication ()
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COA
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