Anti-ATP5I monoclonal antibody, clone 2F7

Antibody Isotype

IgG2a

Clone

2F7

Species Reactivity

Human

Immunogen

ATP5I (AAH03679, 1 a.a. ~ 70 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Alternative Names

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E; MGC12532; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E; ATP synthase e chain, mitochondrial; ATP5K; ATP synthase subunit e, mitochondrial; ATPase subunit e; F1F0-ATP

Entrez Gene ID

UniProt ID

Antigen Description

Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the e subunit of the Fo complex. Alternative splicing results in multiple transcript variants.
Mouse monoclonal antibody raised against a full length recombinant ATP5I.

Pathway

Electron Transport Chain, organism-specific biosystem; Formation of ATP by chemiosmotic coupling, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Oxidative phosphorylation, organism-specific biosystem; Oxidative phosphorylation, organism-specific biosystem; Oxidative phosphorylation, conserved biosystem