Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
antigen sequence: RRIAAEEKKKQDELKRIARELAEDDSILK, corresponding to amino acids 41-69 of Human ATP5I.
Applications
Application Notes
ICC/IF: 1 - 4 μg/ml; IHC-P: 1/200 - 1/500; WB: 1/250 - 1/500.
Target
Alternative Names
ATP5I; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit e; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit E; ATP synthase subunit e, mitochondrial; ATPas
Product Background
Antigen Description
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
Pathway
Electron Transport Chain; F-type ATPase, eukaryotes; Formation of ATP by chemiosmotic coupling; Metabolic pathways; Metabolism; Oxidative phosphorylation;
Citations
Publication ()
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