Specificity
Widely expressed in normal and in cancer cells.
Tag/Conjugate
Unconjugated
SequenceSimilarities
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Antigen Description
The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2009]
Function
mevalonate transmembrane transporter activity; monocarboxylic acid transmembrane transporter activity; organic cyclic compound binding; protein homodimerization activity; secondary active monocarboxylate transmembrane transporter activity; symporter activ
Synonyms
SLC16A1; solute carrier family 16 (monocarboxylate transporter), member 1; MCT; HHF7; MCT1; monocarboxylate transporter 1; MCT 1; solute carrier family 16 member 1; solute carrier family 16 (monocarboxylic acid transporters), member 1; solute carrier family 16, member 1 (monocarboxylic acid transporter 1);
Citations
Publication ()
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COA
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