Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
A synthetic peptide corresponding to residues in Human Myosin Light Chain 3
Applications
Application Notes
Recommended dilution
WB: 1/1000 - 1/10000; IHC-P: 1/100 - 1/250.
Target
Alternative Names
MYL3; myosin, light chain 3, alkali; ventricular, skeletal, slow; myosin, light polypeptide 3, alkali; ventricular, skeletal, slow; myosin light chain 3; CMH8; MLC1SB; MLC1V; VLC1; Cardiac myosin light chain 1; slow-twitch muscle B/ventricular isoform; CM
Product Background
Antigen Description
MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy.
Pathway
Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem; Hypertrophic cardiomyopathy (HCM), organism-specific biosystem; Hypertrophic cardiomyopathy (HCM), conserved biosystem; Muscle contraction, organism-specific biosystem; Regulation of Actin Cytoskeleton, organism-specific biosystem; Striated Muscle Contraction, organism-specific biosystem; Striat
Citations
Publication ()
Have you cited CABT-38817RH in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
