Anti-MLYCD (aa 90-274) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Mouse; Human

Immunogen

Recombinant protein fragment containing a sequence corresponding to a region within amino acids 90-274 of MLYCD (Human).

Conjugate

Application Notes

WB: 1:500-1:3000
IHC-P: 1:100-1:500
ICC/IF: 1:100-1:200

Alternative Names

MLYCD; malonyl-CoA decarboxylase; malonyl-CoA decarboxylase, mitochondrial; hMCD; MCD; hMCD; Malonyl CoA decarboxylase; Malonyl CoA decarboxylase mitochondrial; Malonyl coenzyme A decarboxylase; MCD; MGC59795; malonyl coenzyme A decarboxylase;

Entrez Gene ID

UniProt ID

Antigen Description

The product of this gene catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency.

Pathway

Malonate semialdehyde pathway, propanoyl-CoA => Acetyl-CoA, organism-specific biosystem; Malonate semialdehyde pathway, propanoyl-CoA => Acetyl-CoA, conserved biosystem; Metabolic pathways, organism-specific biosystem; Peroxisome, organism-specific biosystem; Peroxisome, conserved biosystem; Propanoate metabolism, organism-specific biosystem; Propanoate metabolism, conserved biosystem; beta-Alanine metabolism, organism-specific biosystem; beta-Alanine metabolism, conserved biosystem;