Specifications
Immunogen
A synthetic peptide of human MLYCD is used for rabbit immunization.
Target
Alternative Names
MLYCD; malonyl-CoA decarboxylase; malonyl-CoA decarboxylase, mitochondrial; hMCD; MCD; malonyl coenzyme A decarboxylase; MGC59795;
Product Background
Antigen Description
The product of this gene catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency.
Pathway
Malonate semialdehyde pathway, propanoyl-CoA => Acetyl-CoA, organism-specific biosystem; Acetyl-CoA, conserved biosystem; Metabolic pathways, organism-specific biosystem; Peroxisome, organism-specific biosystem; Peroxisome, conserved biosystem.
Citations
Publication ()
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COA
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