Human MARCH2 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-MARCH2/MARCH-II antibody

Target

MARCH2 / MARCH-II

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]; Nakamura et al., 2005 [PubMed 15689499]).[supplied by OMIM, Mar 2010]

Function

ubiquitin-protein ligase activity; zinc ion binding;

Synonyms

MARCH2; membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase; RNF172; HSPC240; MARCH-II; E3 ubiquitin-protein ligase MARCH2; RING finger protein 172; membrane-associated RING-CH protein II; membrane-associated RING finger protein 2;