A synthetic peptide of human MARCH2 is used for rabbit immunization.
Conjugate
Unconjugated
Target
Alternative Names
MARCH2; membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase; RNF172; HSPC240; MARCH-II; E3 ubiquitin-protein ligase MARCH2; RING finger protein 172; membrane-associated RING-CH protein II; membrane-associated RING finger protein 2;
MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]; Nakamura et al., 2005 [PubMed 15689499]).[supplied by OMIM, Mar 2010]
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