Synthetic Human LPIN1 blocking peptide for Apuri, BL, ELISA
Blocking/Immunizing peptide for anti-Lipin 1 (Internal) antibody
Human, Mouse, Dog
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Shipped at ambient temperature, store at -20°C.
This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined. [provided by RefSeq, May 2012]
hydrolase activity; molecular_function; phosphatidate phosphatase activity;
LPIN1; lipin 1; phosphatidate phosphatase LPIN1; KIAA0188; lipin-1; PAP1; DKFZp781P1796;