Rat LGI1 peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

14 amino acids near the center of human LGI1.

Purity

> 95 % by SDS-PAGE.

Format

Lyophilized

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Reconstitution

LGI1 peptide is supplied as 1mg of dried peptide. When the peptide is reconstituted in 1 mL strile water, the concentration will be 1 mg/mL.

Introduction

This gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic segment representing a putative transmembrane domain with the amino terminus located outside the cell. It also contains leucine-rich repeats with conserved cysteine-rich flanking sequences. This gene is predominantly expressed in neural tissues and its expression is reduced in low grade brain tumors and significantly reduced or absent in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. [provided by RefSeq, Jul 2008]

Entrez Gene ID

Synonyms

LGI1; leucine-rich, glioma inactivated 1; EPT; ETL1; ADLTE; ADPAEF; ADPEAF; IB1099; EPITEMPIN; leucine-rich glioma-inactivated protein 1; epitempin-1;