Fusion protein corresponding to Mouse Lgi1 aa 37-113. (LRRNT domain and first LRR repeat)Sequence: PAKPKCPAVCTCSKDNALCENARSIPRTVPPDVISLSFVRSGFTEISEGS FLFTPSLQLLLFTSNSFDVISDDAFIG Database link: Q9JIA1
Conjugate
HRP
Applications
Application Notes
WB: 1/1000;
Target
Alternative Names
LGI1; leucine-rich repeat LGI family, member 1; leucine-rich glioma-inactivated protein 1; leucine-rich, glioma inactivated 1; BB130740;
Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.
Citations
Publication ()
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COA
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