Product Overview
Blocking/Immunizing peptide for anti-LGR7 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Function
G-protein coupled receptor activity; hormone binding; metal ion binding; protein binding;
Synonyms
RXFP1; relaxin/insulin-like family peptide receptor 1; LGR7; RXFPR1; relaxin receptor 1; leucine-rich repeat-containing G protein-coupled receptor 7;
Citations
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Parry, LJ; Vodstrcil, LA; et al. Normal mammary gland growth and lactation capacity in pregnant relaxin-deficient mice. REPRODUCTION FERTILITY AND DEVELOPMENT 21:549-560(2009).
Yao, LJ; Agoulnik, AI; et al. Relative Roles of the Epithelial and Stromal Tissue Compartment(s) in Mediating the Actions of Relaxin and Estrogen on Cell Proliferation and Apoptosis in the Mouse Lower Reproductive Tract. RELAXIN AND RELATED PEPTIDES: FIFTH INTERNATIONAL CONFERENCE 1160:121-129(2009).