This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Function
G-protein coupled receptor activity; hormone binding; metal ion binding; protein binding;
Synonyms
RXFP1; relaxin/insulin-like family peptide receptor 1; LGR7; RXFPR1; relaxin receptor 1; leucine-rich repeat-containing G protein-coupled receptor 7;
Citations
Publication ()
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