Product Overview
Blocking/Immunizing peptide for anti-LGP2 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
DHX58 (DEXH (Asp-Glu-X-His) box polypeptide 58) is a protein-coding gene. Diseases associated with DHX58 include rabies, and mumps, and among its related super-pathways are RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways. GO annotations related to this gene include double-stranded RNA binding and single-stranded RNA binding. An important paralog of this gene is IFIH1.
Function
ATP binding; DNA binding; RNA binding; helicase activity; hydrolase activity, acting on acid anhydrides; metal ion binding; nucleotide binding; protein binding; zinc ion binding;
Synonyms
DHX58; DEXH (Asp-Glu-X-His) box polypeptide 58; probable ATP-dependent RNA helicase DHX58; D11LGP2; LGP2; RNA helicase LGP2; RLR; protein D11Lgp2 homolog; RIG-I-like receptor LGP2; ortholog of mouse D11lgp2; probable ATP-dependent helicase LGP2; D11lgp2e;
Citations
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Li, XY; Han, CM; et al. Expression patterns and association analysis of the porcine DHX58 gene. ANIMAL GENETICS 41:537-540(2010).
Rise, ML; Hall, JR; et al. Impact of asymptomatic nodavirus carrier state and intraperitoneal viral mimic injection on brain transcript expression in Atlantic cod (Gadus morhua). PHYSIOLOGICAL GENOMICS 42:266-280(2010).