Human RNF103 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-KF1/ZFP103 antibody

Target

KF1 / ZFP103

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

The protein encoded by this gene contains a RING-H2 finger, a motif known to be involved in protein-protein and protein-DNA interactions. This gene is highly expressed in normal cerebellum, but not in the cerebral cortex. The expression of the rat counterpart in the frontal cortex and hippocampus was shown to be induced by elctroconvulsive treatment (ECT) as well as chronic antidepressant treatment, suggesting that this gene may be a molecular target for ECT and antidepressants. The protein is a ubiquitin ligase that functions in the endoplasmic reticulum-associated degradation pathway. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream CHMP3 (charged multivesicular body protein 3) gene. [provided by RefSeq, Oct 2011]

Function

protein binding; ubiquitin-protein ligase activity; zinc ion binding;

Synonyms

RNF103; ring finger protein 103; KF1; KF-1; HKF-1; ZFP103; ZFP-103; E3 ubiquitin-protein ligase RNF103; zinc finger protein 103 homolog; zinc finger protein expressed in cerebellum;