Human KCNN2 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-KCNN2 antibody

Target

KCNN2

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]

Function

calmodulin binding; ion channel activity; potassium channel activity; small conductance calcium-activated potassium channel activity; small conductance calcium-activated potassium channel activity;

Synonyms

KCNN2; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2; small conductance calcium-activated potassium channel protein 2; hSK2; KCa2.2; SKCa 2; apamin-sensitive small-conductance Ca2+-activated potassium channel; SK2; SKCA2;