Human KCNN2 blocking peptide (CDBP1675)

Synthetic Human KCNN2 blocking peptide for Apuri, BL, ELISA Datasheet

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Product Overview
Blocking/Immunizing peptide for anti-KCNN2 antibody
Target
KCNN2
Nature
Synthetic
Species Reactivity
Human, Mouse, Cow, Dog, Rat
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Size
100 μg
Storage
Shipped at ambient temperature, store at -20°C.
UniProt ID
Antigen Description
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
Function
calmodulin binding; ion channel activity; potassium channel activity; small conductance calcium-activated potassium channel activity; small conductance calcium-activated potassium channel activity;
Synonyms
KCNN2; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2; small conductance calcium-activated potassium channel protein 2; hSK2; KCa2.2; SKCa 2; apamin-sensitive small-conductance Ca2+-activated potassium channel; SK2; SKCA2;

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