Synthetic peptide: C-ESYDKHVTYNAER, corresponding to internal amino acids 546 - 557 of Human KCNN2 (NP_067627.2) and 197 - 209 of Human KCNN2 isoform b (NP_740721.1).
Conjugate
Unconjugated
Target
Alternative Names
KCNN2; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2; small conductance calcium-activated potassium channel protein 2; hSK2; KCa2.2; SKCa 2; apamin-sensitive small-conductance Ca2+-activated potassium channel; S
Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.
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