Rabbit Anti-Human KCNN1 Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

A synthesized peptide derived from human KCNN1

Conjugate

Application Notes

WB: 1:500-1:2000

General Notes

This product (Catalog No. CABT-BL2016) is a rabbit-derived polyclonal antibody raised against human KCNN1. This antibody exhibits cross-reactivity with KCNN1 from mouse and rat. It has been affinity purified by Protein A. Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes.
CABT-BL2016 is suitable for use in Western blot (WB) (1:500–1:2,000) application.
CABT-BL2016 is supplied as a liquid formulation in PBS containing 50% glycerol, and 0.02% sodium azide. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

hSK1 antibody KCa2.1 antibody KCNN 1 antibody Kcnn1 antibody KCNN1_HUMAN antibody Potassium intermediate/small conductance calcium activated channel subfamily N member 1 antibody SK antibody SK1 antibody SKCa 1 antibody SKCA1 antibody Small conductance calcium activated potassium channel protein 1 a

Entrez Gene ID

UniProt ID