Human KCNJ1 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-KCNJ1/ROMK antibody

Target

KCNJ1 / ROMK

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function

ATP binding; inward rectifier potassium channel activity; nucleotide binding; voltage-gated ion channel activity;

Synonyms

KCNJ1; potassium inwardly-rectifying channel, subfamily J, member 1; ATP-sensitive inward rectifier potassium channel 1; Kir1.1; ROMK1; inwardly rectifying K+ channel; inward rectifier K(+) channel Kir1.1; ATP-regulated potassium channel ROM-K; potassium channel, inwardly rectifying subfamily J member 1; ROMK; KIR1.1;