CD82 blocking peptide (CDBP5629)

Nature
Synthetic
Immunogen
15 amino acids near the carboxy terminus of human KAI1
Species Reactivity
Rat, human, mouse
Tag/Conjugate
Unconjugated
Procedure
None
Format
Liquid
Concentration
200 μg/mL
Size
0.05mg
Preservative
None
Storage
-20°C
UniProt ID
Antigen Description
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function
protein binding
Synonyms
CD82; CD82 molecule; R2; 4F9; C33; IA4; ST6; GR15; KAI1; SAR2; TSPAN27; CD82 antigen; tspan-27; C33 antigen; tetraspanin-27; inducible membrane protein R2; metastasis suppressor Kangai-1; kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4))

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