Specificity
In airway epithelium, in the basal layer of squamous epithelium, and in smooth muscle, skeletal muscle, and hepatocytes. Abundantly expressed in fetal lung and lung cancers.
Tag/Conjugate
Unconjugated
SequenceSimilarities
Belongs to the integrin alpha chain family.Contains 7 FG-GAP repeats.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Antigen Description
This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. [provided by RefSeq, Jul 2008]
Function
collagen binding; laminin binding; metal ion binding;
Synonyms
ITGA9; integrin, alpha 9; RLC; ITGA4L; ALPHA-RLC; integrin alpha-9; integrin alpha-RLC;
Citations
Publication ()
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COA
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