Specifications
Immunogen
ITGA9 (NP_002198, 785 a.a. ~ 886 a.a) partial recombinant protein with GST tag. The sequence is GESVDAANFIQLDDLECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQ EMVVGQEKGNCSFQKNPTPCIIPQEQENIFHTIFAFFTKSGR
Target
Alternative Names
ITGA9; integrin, alpha 9; RLC; ITGA4L; ALPHA-RLC; integrin alpha-9; integrin alpha-RLC;
Product Background
Antigen Description
This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers.
Pathway
Arrhythmogenic right ventricular cardiomyopathy; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Cell adhesion molecules (CAMs); Developmental Biology
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Masia, A; Almazan-Moga, A; et al. Notch-mediated induction of N-cadherin and alpha 9-integrin confers higher invasive phenotype on rhabdomyosarcoma cells. BRITISH JOURNAL OF CANCER 107:1374-1383(2012).
Guo, XC; Winkler, CA; et al. Evaluation and Integration of Genetic Signature for Prediction Risk of Nasopharyngeal Carcinoma in Southern China. BIOMED RESEARCH INTERNATIONAL :-(2014).
COA
Certificate of Analysis
