General Notes
This product (Catalog No. CABT-BL1886) is a rabbit-derived polyclonal antibody raised against human IER5L. This antibody exhibits cross-reactivity with IER5L from mouse and rat. It has been affinity purified by Protein A. Immediate Early Response 5 Like (IER5L) is a protein-coding gene and member of the IER family that acts as a crucial regulator of Protein Phosphatase 2A (PP2A) activity, influencing cancer progression and prognosis. It is frequently upregulated in various cancers, including non-small cell lung cancer (NSCLC) and prostate cancer, where it promotes proliferation, migration, and metastasis by modulating cell cycle regulators like CDC25A.
CABT-BL1886 is suitable for use in IF/ICC 1 (100-1:500), IHC 1 (50-1:200) applications.
CABT-BL1886 is supplied as a liquid formulation in Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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