Anti-IDH2 monoclonal antibody (DMABT-H14002)

Mouse anti-Human IDH2 monoclonal antibody for WB, IHC, sELISA, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
6G22
Species Reactivity
Human
Immunogen
IDH2 (NP_002159, 354 a.a. ~ 451 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
IDH2; isocitrate dehydrogenase 2 (NADP+), mitochondrial; isocitrate dehydrogenase [NADP], mitochondrial; NADP(+)-specific ICDH; oxalosuccinate decarboxylase; IDH
Entrez Gene ID
UniProt ID

Product Background


Pathway
Citrate cycle (TCA cycle), organism-specific biosystem; Citrate cycle (TCA cycle), conserved biosystem; Citrate cycle, first carbon oxidation, oxaloacetate =>2-oxoglutarate, organism-specific biosystem; Citrate cycle, first carbon oxidation, oxaloacetate =>2-oxoglutarate, conserved biosystem; Citric acid cycle (TCA cycle), organism-specific biosystem;

Citations


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References


Frenel, JS; Leux, C; et al. Combining two biomarkers, IDH1/2 mutations and 1p/19q codeletion, to stratify anaplastic oligodendroglioma in three groups: a single-center experience. JOURNAL OF NEURO-ONCOLOGY 114:85-91(2013).
Shah, MV; Barochia, A; et al. Impact of Genetic Targets on Cancer Therapy in Acute Myelogenous Leukemia. IMPACT OF GENETIC TARGETS ON CANCER THERAPY 779:405-437(2013).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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