Specifications
Applications
Application Notes
ELISA, FuncS
Each laboratory should determine an optimum working titer for use in its particular application.
Other applications have not been tested but use in such assays should not necessarily be excluded.
General Notes
Clone 2Q1 targets IDH2(R140Q) mutant peptide in complex with a common HLA allele (HLA-B07:02). It selectively bounds IDH2R140Q but not IDH2WT.
Images
Characterization of IDH2R140Q-HLA-B*07:02 scFvs identified by
phage display technology. The data shows that 2Q1 bounds IDH2R140Q but not IDH2WT.
Target
Alternative Names
IDH; IDP; ICD-M; IDHM; mNADP-IDH; Isocitrate dehydrogenase [NADP], mitochondrial; Oxalosuccinate decarboxylase
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Frenel, JS; Leux, C; et al. Combining two biomarkers, IDH1/2 mutations and 1p/19q codeletion, to stratify anaplastic oligodendroglioma in three groups: a single-center experience. JOURNAL OF NEURO-ONCOLOGY 114:85-91(2013).
Sahm, F; Capper, D; et al. Detection of 2-Hydroxyglutarate in Formalin-Fixed Paraffin-Embedded Glioma Specimens by Gas Chromatography/Mass Spectrometry. BRAIN PATHOLOGY 22:26-31(2012).
COA
Certificate of Analysis
