Human Urine β2-MICROGLOBULIN

Product Overview

Protein purified fromHuman urine (patients with chronic renal tubular proteinuria)

Nature

Native

Tag/Conjugate

Unconjugated

Purity

> 98% by SDS PAGE and Cellulose Acetate Electrophoresis.

Format

Lyophilized from0.02M Ammonium Bicarbonate (may contain traces o buffer salt).

Preservative

None

Storage

2-8°C short term, -20°C long term

Introduction

This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.

Keywords

B2M; beta-2-microglobulin; Beta-2-microglobulin; beta chain of MHC class I molecules; beta-2-microglobin; β2-MG