Product Overview
Protein purified fromHuman urine (patients with chronic renal tubular proteinuria)
Tag/Conjugate
Unconjugated
Purity
> 98% by SDS PAGE and Cellulose Acetate Electrophoresis.
Format
Lyophilized from0.02M Ammonium Bicarbonate (may contain traces o buffer salt).
Storage
2-8°C short term, -20°C long term
Introduction
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
Keywords
B2M; beta-2-microglobulin; Beta-2-microglobulin; beta chain of MHC class I molecules; beta-2-microglobin; β2-MG
Citations
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Li, XY; Yang, QW; et al. Identification of optimal reference genes for quantitative PCR studies on human mesenchymal stem cells. MOLECULAR MEDICINE REPORTS 11:1304-1311(2015).
Vianello, A; Caponi, L; et al. beta(2)-Microglobulin and TIMP1 Are Linked Together in Cardiorenal Remodeling and Failure. CARDIORENAL MEDICINE 5:1-11(2015).
COA
Certificate of Analysis
