Product Overview
Recombinant Leech Hirudin
Tag/Conjugate
Unconjugated
Purity
Greater than 95.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Format
Sterile Filtered White lyophilized (freeze-dried) powder.
Storage
2-8°C short term, -20°C long term
Introduction
Hirudin is a naturally occurring peptide in the salivary glands of medicinal leeches (such as Hirudo medicinalis) that has a blood anticoagulant property. This is fundamental for the leeches' alimentary habit of hematophagy, since it keeps the blood flowing after the initial phlebotomy performed by the worm on the host's skin.
Keywords
Hirudin; Hirudin 1; Lepirudin; Refludan
Citations
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Walenga, JM; Prechel, M; et al. Apixaban as an Alternate Oral Anticoagulant for the Management of Patients With Heparin-Induced Thrombocytopenia. CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS 19:482-487(2013).
Magee, AN; Hogan, DE; et al. In vitro effects of the glycoprotein IIb/IIIa receptor antagonists abciximab and eptifibatide on platelet aggregation in healthy cats. AMERICAN JOURNAL OF VETERINARY RESEARCH 75:309-312(2014).
COA
Certificate of Analysis
