Product Overview
Blocking/Immunizing peptide for anti-Hand2 (zebrafish) antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development. [provided by RefSeq, Jul 2008]
Function
DNA binding; protein dimerization activity;
Synonyms
HAND2; heart and neural crest derivatives expressed transcript 2; dhand; zdHAND; zgc:103415; heart- and neural crest derivatives-expressed protein 2; han; hands off; deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2;
Citations
Publication ()
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