Anti-HMGB2 monoclonal antibody (DMABT-H13962)
Mouse anti-Human HMGB2 monoclonal antibody for WB, IHC, IF, sELISA, ELISA
Datasheet
Specifications
Host Species
Mouse
Antibody Isotype
IgG2a
Clone
4E3
Species Reactivity
Human
Immunogen
HMGB2 (AAH00903.2,2a.a. ~206a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
Target
Alternative Names
HMGB2; high mobility group box 2; high mobility group (nonhistone chromosomal) protein 2 , high mobility group box 2 , HMG2; high mobility group protein B2; HMG-2; high-mobility group box 2
Entrez Gene ID
UniProt ID
Product Background
Pathway
Activation of DNA fragmentation factor, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis induced DNA fragmentation, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem;
Citations
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References
Uchimura, T; Motomiya, Y; et al. High mobility group box-1 (HMGB1) is a major target antigen of perinuclear anti-neutorophil cytoplasmic antibodies (PANCA) in maintenance hemodialysis patients.. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 14:227A-227A(2003).
Kim, SW; Lim, CM; et al. Extracellular HMGB1 Released by NMDA Treatment Confers Neuronal Apoptosis via RAGE-p38 MAPK/ERK Signaling Pathway. NEUROTOXICITY RESEARCH 20:159-169(2011).
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Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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