HIV Glycoprotein 41 (DAG-P2669)

HIV Glycoprotein 41 (full length), recombinant protein from E. coli Datasheet

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Product Overview
HIV gp41 full length protein
Nature
Recombinant
Tag/Conjugate
Unconjugated
Format
Liquid
Buffer
Preservative: 0.01% Sodium Azide Constituents: 50% Glycerol, 1.5M Urea, 25mM Tris HCl, 1mM EDTA
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. Preservative: 0.01% Sodium Azide Constituents: 50% Glycerol, 1.5M Urea, 25mM Tris HCl, 1mM EDTA
Introduction
The human immunodeficiency virus (HIV) is a lentivirus (slowly replicating retrovirus) that causes the acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic
Antigen Description
gp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.
Keywords
HIV gp41

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