Human PHC2 peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

Contains 1 FCS-type zinc finger.Contains 1 SAM (sterile alpha motif) domain.

Alternative Names

HD1 motif interacts with SAM domain of PHC1.

Format

Liquid

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Entrez Gene ID

Antigen Description

In Drosophila melanogaster, the Polycomb group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein polyhomeotic (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function

DNA binding; protein binding; zinc ion binding;

Synonyms

PHC2; polyhomeotic homolog 2 (Drosophila); PH2; EDR2; HPH2; polyhomeotic-like protein 2; polyhomeotic 2; polyhomeotic-like 2; early development regulatory protein 2; early development regulator 2 (homolog of polyhomeotic 2);